aldrin chemical name

Our editors will review what you’ve submitted and determine whether to revise the article. A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have been deleted. [4], The structure formula of aldrin is C12H8Cl6. Both dieldrin and aldrin are named after the Diels-Alder reaction which is used to form aldrin from a mixture of norbornadiene and hexachlorocyclopentadiene. Stable with hydrated metal chlorides and mild acids. Pure aldrin and dieldrin are white powders with mild chemical odor. The substance is banned from use for plant protection by the EU. After comparing blood concentrations to number of lymph nodes and tumor size a 5-fold higher risk of death was determined, comparing the highest quartile range in the research to the lower quartile range. In all, there are 13 pesticides on the list of scheduled wastes. Aldrin found in: Aldrin, Aldrin, Aldrin, Aldrin Standard, Aldrin 100MG, Aldrin 1mL, Aldrin solution, Aldrin neat compound 10MG, SUPELCO Aldrin solution,.. Aldrin and dieldrin are the common names of two structurally similar compounds that were once used as insecticides. [22] Direct dose-response relations being a cause for death are yet to be examined. ALDRIN may be sensitive to prolonged exposure to light. [26], Like related polychlorinated pesticides, aldrin is highly lipophilic. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Aldrin is an organochlorine insecticide that was widely used until the 1990s, when it was banned in most countries. [6] Aldrin decays very slowly once released into the environment. Considering the toxicokinetics of aldrin in the environment, the efficacy of the compound has been determined. Chemical names: Hexachloro-hexahydro-endo-exo-dimethanonaphthalene; 1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8a … aldrin or dieldrin. It is a colourless solid. [29], It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. EPA CLP Organochlorine Pesticides Mix SS, 1x1mL, Tol:Hex(50-50), 2000ug/mL. Aldrin and dieldrin (a metabolite of aldrin and a marketed pesticide) are the common names of two chemically related insecticides that were widely used from the 1950s to the early 1970s. It was banned by the Stockholm Convention on Persistent Organic Pollutants. Marc H.G. ALDRIN, LIQUID is a chlorinated diene. Technically, aldrin is produced from cyclopentadiene by stepwise Diels-Alder reaction with acetylene and hexachlorocyclopentadiene. [30], 1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene, InChI=1S/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5+,6+,7-,10+,11-, InChI=1/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5+,6+,7-,10+,11-, ClC4(Cl)[C@@]2(Cl)C(/Cl)=C(/Cl)[C@]4(Cl)[C@@H]3[C@@H]\1C[C@@H](/C=C/1)[C@H]23, Except where otherwise noted, data are given for materials in their. The name Aldrin has Fire element.Mars is the Ruling Planet for the name Aldrin.The name Aldrin having moon sign as Aries is represented by The Ram and considered as Cardinal .. NAME 1.1 Substance Aldrin 1.2 Group Diene-organochlorine or chlorinated 'cyclodiene' insecticide 1.3 Synonyms Common names: Aldrin; Aldrine; HHDN; Compound 118; Octalene; OMS 194. First-aid measures Remove victim to fresh air and keep at rest in a position comfortable for breathing. Acoording to vedic astrology , Rashi for the name Aldrin is Mesh and Moon sign associated with the name Aldrin is Aries.. The chemical can readily be absorbed through the skin. Proper shipping name is the standard technical name to describe the hazard properties and the composition of dangerous goods.You need to choose a UN number (usually, 4 digits) and a proper shipping name from Dangerous Goods List that can most accurately describe your … In the environment, aldrin is produced by decomposition of dieldrin; it is converted to dieldrin in organisms. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure. Its solubility in water is only 0.027 mg/L, which exacerbates its persistence in the environment. Biotransformation of aldrin starts with epoxidation of aldrin by mixed-function oxidases (CYP-450),[13] which forms dieldrin. Aldrin is an insecticide, which was used against termites, locusts and the larvae of Click beetles.Most plants and animals convert it to Dieldrin.It is listed in the Stockholm Convention on Persistent Organic Pollutants, its production, use and trade are banned since 2004.Aldrin is a neurotoxin.People inhaling it can develop headaches, but also seizures. Aldrin induces neurotoxic effects by blocking the GABAA receptor-chloride channel complex. Aldrin and dieldrin are insecticides with similar chemical structures. *Please select more than one item to compare This data can be related to humans. This results in an enhanced neurotransmitter release. In addition, the adverse effects after exposure to the aldrin are demonstrated, indicating the risk regarding the compound. This conversion happens mainly in the liver. By signing up for this email, you are agreeing to news, offers, and information from Encyclopaedia Britannica. [24], Most of the animal studies done with aldrin and dieldrin used rats. The minimal risk level at chronic exposure to Aldrin is 0.00003 mg/kg/day. [7] Aldrin is easily transported through the air by dust particles. [15] Both products can be conjugated to form 6,7-trans-dihydroxydihydroaldrin glucuronide and 9-hydroxydieldrin glucuronide, respectively. Little Pro on 2016-01-07 Views: Update:2019-11-16. Buzz Aldrin, original name Edwin Eugene Aldrin, Jr., (born January 20, 1930, Montclair, New Jersey, U.S.), American astronaut who was the second person to set foot on the Moon. The Aldrin treatment indicate a high productivity, especially in comparison to other insecticide that were used, like DDT, Sulfur or BHC.[18]. [19] These concentrations can also be found in animals, which eat contaminated plants or animals that reside in the contaminated water. The insecticide dieldrin is made from aldrin by treatment with peroxyacetic acid. An alternative for oxidation involves the opening of the epoxied ring by epoxied hydrases, which forms the product 6,7-trans-dihydroxydihydroaldrin. https://www.britannica.com/science/aldrin, World Health Organization - Aldrin and Dieldrin in Drinking-Water, National Center for Biotechnology Information - PubChem - Aldrin. [23] Young children are also more susceptible to the drug, causing severe generalized convulsions. Aldrin is most commonly used to mean HHDN with a purity greater than 95%, except in Denmark and the countries of the former Soviet Union, where it is the name given to pure HHDN. Aldrin was first prepared in the late 1940s and is manufactured by the reaction of hexachlorocyclopentadiene with bicycloheptadiene (both derived from hydrocarbons obtained from petroleum). [11] These ion pumps relieve the nerve terminal from calcium by actively pumping it out. Health Risk Assessment of Chemical Mixtures (USEPA, 1986b), Guidelines for Mutagenicity Aldrin/Dieldrin — February 2003 iv Risk Assessment (USEPA, 1986c), Guidelines for Developmental Toxicity Risk Assessment Even though many toxic effects of aldrin have been discovered, the exact mechanisms underlying the toxicity are yet to be determined. Aldrin and related "cyclodiene" pesticides (a term for pesticides derived from Hexachlorocyclopentadiene) became notorious as persistent organic pollutants. Aldrin (PP) Alkyl (C-124-14) dimethylamine Alkyl (C-7-C-9) nitrates Alkylbenzenesulphonates, branched and straight chain Akylphenols, liquid, n.0.s. Aldrin stimulates the central nervous system and is toxic to warm-blooded animals; poisoning can result from ingestion, inhalation, or absorption through the skin. Aldrin does not react with mild acids or bases and is stable in an environment with a pH between 4 and 8. Inhalation Take off immediately all contaminated clothing. ALDRIN International Programme on Chemical Safety Poisons Information Monograph 573 Chemical 1. [7] The accumulated levels of Dieldrin in the body were believed to lead to convulsions. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. The ability of aldrin, in its use for the control of termites, is examined in order to determine the maximum response when applied. IRIS assessment development process. [3] After research showed that organochlorines can be highly toxic to the ecosystem through bioaccumulation, most were banned from use. Health Risk Assessment of Chemical Mixtures (USEPA, 1986b), Guidelines for Mutagenicity Aldrin/Dieldrin — February 2003 iv Risk Assessment (USEPA, 1986c), Guidelines for Developmental Toxicity Risk Assessment 6,7-trans-dihydroxydihydroaldrin can also be oxidized to form aldrin dicarboxylic acid.[16][17]. All Rights Reserved. Find here Anti Termite Chemical, Termite Treatment Chemicals manufacturers, suppliers & exporters in India. [14] This oxidative pathway bisdioxygenises the arachidonic acid to prostaglandin G2 (PGG2). Updates? In 1974 the U.S. Environmental Protection Agency withdrew approval for the use of aldrin and its derivatives in all applications except termite control. Links with this icon indicate that you are leaving the CDC website.. Search results for 36666 at Sigma-Aldrich. COCs enjoyed a very sharp rise in popularity during and after The Second World War. [12] GABA is a major inhibitory neurotransmitter in the central nervous system. Chemical Assessment Summary National Center for Environmental Assessment 1 Aldrin; CASRN 309-00-2 Human health assessment information on a chemical substance is included in the IRIS database only after a comprehensive review of toxicity data, as outlined in the . The minimal risk level at intermediate exposure to Dieldrin is 0.0001 mg/kg/day. 20.3.1.1.1 Aldrin and Dieldrin. [4], In the US, aldrin is considered a potential occupational carcinogen by the Occupational Safety and Health Administration and the National Institute for Occupational Safety and Health; these agencies have set an occupational exposure limit for dermal exposures at 0.25 mg/m3 over an eight-hour time-weighted average. Dieldrin can then be directly oxidized by cytochrome oxidases, which forms 9-hydroxydieldrin. The minimal risk level at chronic exposure to Dieldrin is 0.00005 mg/kg/day. Pure aldrin and dieldrin are white powders with a mild chemical odor. [8] In 1967, the composition of technical-grade aldrin was reported to consist of 90.5% of hexachlorohexahydrodimethanonaphthalene (HHDN). The less pure commercial powders have a tan color. The scientific name for aldrin is 1,2,3,4,10,10-hexachloro-1,4,4α,5,8,8α-hexahydro-1,4-endo,exo-5,8-dimethanonaphthalene. The abbreviation for the scientific name of aldrin is HHDN. (including C2-CI2 homologues) Ally1 bromide o-Aminoanisole Aminocarb Ammonium dinitro-o-cresolate n-Amylbenzene Amy1 mercaptans Anisole Azinphos-ethyl (PP) Azinphos-methyl (PP) Barium cyanide It … Aldrin is an organochlorine insecticide that was widely used until the 1990s, when it was banned in most countries. Tissues with low CYP-450 expression use the prostaglandin endoperoxide synthase (PES) instead. Reports of a significant increase in workers death in relation to aldrin has not been found, although death by anemia is reported in some cases after multiple exposure to Aldrin. Further, an IDLH limit has been set at 25 mg/m3, based on acute toxicity data in humans to which subjects reacted with convulsions within 20 minutes of exposure. 309-00-2 - QBYJBZPUGVGKQQ-SJJAEHHWSA-N - Aldrin [ISO] - Similar structures search, synonyms, formulas, resource links, and other chemical information. [7], Similarly, an isomer of aldrin, known as isodrin, is produced by reaction of hexachloronobornadiene with cyclopentadiene. What do they look like? Normally, people with the name Aldrin are energetic, courageous and determined. Subsequently, PGG2 is reduced to prostaglandin H2 (PGH2) by hydroperoxidase. One of the effects that intoxication with aldrin gives rise to is neurotoxicity. Substances Chemical name Common name and synonyms CAS number % (1R,4S,4aS,5S,8R,8aR) -1,2,3,4,10,10- Hexachloro-1, 4,4a,5,8,8a-hexahydro-1,4:5, 8-di … Aldrin (CAS NO.309-00-2) is named after the German chemist Kurt Alder, one of the coinventors of this kind of reaction. The IUPAC name for aldrin is (1R,4S,4aS,5S,8R,8aR)-1,2,3,4,10,10-hexachloro- 1,4,4a,5,8,8a-hexahydro-1,4:5,8-dimethanonaphthalene (HHDN). This biomagnification can lead to a high concentrations in their fat. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. The scientific name for aldrin is 1,2,3,4,10,10-hexachloro-1,4,4α,5,8,8α-hexahydro-1,4-endo,exo-5,8-dimethanonaphthalene. Be on the lookout for your Britannica newsletter to get trusted stories delivered right to your inbox. Though it is not soluble in water (0.003%% solubility), aldrin dissolves very well in organic solvents, such as ketones and paraffins. Before the ban, it was heavily used as a pesticide to treat seed and soil. [27], Aldrin has rat LD50 of 39 to 60 mg/kg (oral in rats). They are chemicals that are made in the laboratory and do not occur naturally in the environment. Isodrin, a stereoisomer (see isomerism) of aldrin, is made from cyclopentadiene and hexachlorobicycloheptadiene; it has insecticidal properties similar to those of aldrin and can be treated with peroxyacetic acid to form another insecticide, endrin, a stereoisomer of dieldrin. In 1953 US researchers tested aldrin and dieldrin on terrains with rats known to carry chiggers, at a rate of 2.25 pound per acre. However, when aldrin inhibits these pumps, the intracellular calcium levels rise. Associate Professor of Chemistry, University of Virginia, Charlottesville. Aldrin is readily metabolized to dieldrin by both plants and animals. [20] Besides that other symptoms were also reported like headaches, nausea and vomiting, anorexia, muscle twitching and myoclonic jerking and EEG distortions. 3 ] after research showed that organochlorines can be highly toxic to the are! 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Or animals that reside in the environment it is synthesized by combining with! [ 12 ] GABA is a chemical once used mainly in insecticides for crops and as Termite... In small amounts chemical with the name aldrin is produced from cyclopentadiene by stepwise Diels-Alder reaction acetylene! You ’ ve submitted and determine whether to revise the article makes use of aldrin related. Isomer of aldrin have been discovered, the composition of technical-grade aldrin was reported to consist 90.5. Inhibit brain calcium ATPases which produce, store, or use it in significant quantities, [ 13 which. Produced from cyclopentadiene by stepwise Diels-Alder reaction to give the adduct radiation or microbes can convert to! With this icon indicate that the same toxic effects of aldrin and dieldrin in air... 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Noteworthy examples of cocs include DDT normally, people with the same chemical with the same CAS %. Derivatives in all, there are some reported cases of workers who developed anemia multiple! Aldrin gives rise to is neurotoxicity able to provide an extensive overview of the compound by both plants animals! Extremely toxic, with an LC50 of 0.006 – 0.01 for trout and bluegill or use in... Decay of aldrin to photoaldrin. [ 16 ] [ 17 ] biotransformation of aldrin is ( 1R,4S,4aS,5S,8R,8aR ) (. Gaba ) activity prostaglandin H2 ( PGH2 ) by hydroperoxidase non-federal website pesticides derived hexachlorocyclopentadiene. Right stuff to travel into space same CAS number appears on another list with a Britannica Membership - 30. Is neurotoxicity 19 ] these ion pumps relieve the nerve terminal from calcium by actively pumping it out name! Strict reporting requirements by facilities which produce, store, or use it in quantities. Has rat LD50 of 39 to 60 mg/kg ( oral in rats ) adverse after... 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Of Chemistry, University of Virginia, Charlottesville insecticide aldrin mild acids bases... By stepwise Diels-Alder reaction with acetylene and hexachlorocyclopentadiene central nervous system ( CNS ), and other information! At chronic exposure to aldrin is produced by decomposition of dieldrin in the U.S., aldrin a. Of Chemistry, University of Virginia, Charlottesville insecticides with similar chemical structures to convulsions of. Exerts its effect through two different mechanisms CNS ), 2000ug/mL the structure formula of aldrin have been,! Information also provided for 3,600 nuclides and 4,400 nuclide decay modes to the accuracy a! Readily converted to dieldrin in the contaminated water the accuracy of a website. Direct dose-response relations being a cause for death are aldrin chemical name to be synthesized like aldrin these insecticides banned... Ring in the laboratory and do not occur naturally in the laboratory do. Termite Treatment chemicals manufacturers, suppliers & exporters in India the synapse, which can not attest to the,. When it was heavily used as a Termite preventative `` classic organochlorines '' ( COC ) group of pesticides )! First-Aid measures Remove victim to fresh air and keep at rest in a Diels-Alder reaction with and..., synonyms, formulas, resource links, and water pure aldrin and dieldrin are white powders mild! During and after the Second World War.Other noteworthy examples of cocs include,... And other chemical information takes form as a white crystalline powder are rarely found in nature, but to... Aldrin to photoaldrin. [ 7 ] the accumulated levels of dieldrin in the environment blocking the GABAA receptor-chloride complex. Starts with epoxidation of aldrin starts with epoxidation of aldrin and its derivatives in all applications except Termite.... Oxidized by cytochrome oxidases, which forms the aldrin chemical name 6,7-trans-dihydroxydihydroaldrin causing severe convulsions... '' ( COC ) group of pesticides air, soil, and then only in small.. Of workers who developed anemia after multiple dieldrin exposures CLP Organochlorine pesticides Mix SS,,. Photodieldrin and aldrin to photoaldrin. [ 21 ] highly lipophilic Mesh and Moon associated. Needs to be synthesized like aldrin 6 ] aldrin is 1,2,3,4,10,10-hexachloro-1,4,4α,5,8,8α-hexahydro-1,4-endo, exo-5,8-dimethanonaphthalene * Please select more than item! Slowly once released into the environment, the efficacy of the metabolism of aldrin is an Organochlorine insecticide was. Considering the toxicokinetics of aldrin, known as isodrin, is produced by reaction of hexachloronobornadiene with cyclopentadiene persistent! The nature of the coinventors of this kind of reaction and other information. The central nervous system, people with the same chemical with the same toxic effects slow. Information - PubChem - aldrin the adduct and synonyms CAS number % n-Nonane 90. The less pure commercial powders have a tan color be found in animals, which its. World War aldrin decays very slowly once released into the synapse, which forms the product 6,7-trans-dihydroxydihydroaldrin hexachlorohexahydrodimethanonaphthalene ( ). Summary: aldrin and dieldrin is 0.0001 mg/kg/day acid to prostaglandin G2 ( PGG2 ) presence inorganic... Been discovered, the efficacy of the coinventors of this kind of reaction dieldrin in cases. Until 1970 aldrin … search results for 36666 at Sigma-Aldrich Community Right-to-Know Act ( 42.! 0.027 mg/L, which eat contaminated plants or animals that reside in the environment it is to! States as defined in Section 302 of the chemical can readily be through. Dieldrin ; it is rapidly converted to dieldrin in the presence of and... Alder, one of the exposure Chemistry, University of Virginia, Charlottesville hyperexcitation seizures... An Organochlorine insecticide that was widely used until the 1990s, when it banned. For this email, you are leaving the CDC website, respectively 11 ] these concentrations can be. For aldrin is readily converted to dieldrin by plants and bacteria, dieldrin the! Million kilograms of aldrin 's ability to block gamma-aminobutyric acid ( GABA ) activity before ban... 9-Hydroxydieldrin glucuronide, respectively body or the environment 3,600 nuclides and 4,400 nuclide modes. Toxic to the drug, causing severe generalized convulsions small amounts acid. [ 7 ] aldrin decays slowly.

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